Nucleotide changes in Vibrio parahaemolyticus plasmids isolated from affected shrimp by the acute Hepatopancreatic Necrosis Disease (AHPND) in Tumbes (Peru)

Authors

DOI:

https://doi.org/10.15359/revmar.18-1-3

Keywords:

AHPND, shrimps, plasmids, sequencing, Vibrio parahaemolyticus

Abstract

Although Acute Hepatopancreatic Necrosis Disease (AHPND) causes significant shrimp mortality worldwide, lower mortality rates have been reported in South America. This study analyzed the nucleotide sequences of three plasmids from Vibrio parahaemolyticus strains isolated from infected shrimp in Tumbes, Peru; all sequences are deposited in the GenBank database. The bioinformatic analysis revealed high similarity to the pVA1 plasmid, with complete sequence homology in the genes encoding the PirAB binary toxin in two of the plasmids and a partial deletion in the pirAVP gene in the third. Additionally, all three plasmids harbored mutations in other genes, likely associated with the disease.


Author Biographies

  • Leslie Giovanna Delgado-Olivares, Universidad Nacional Federico Villarreal

    Bachiller en Biología, miembro del Laboratorio de Investigación en Biotecnología, Universidad NAcionall Federico Villarreal, Lima, Perú.

  • Víctor Leonardo Osorio-Guevara, Universidad Nacional Federico Villarreal

    Licenciado en Biología.  Miembro del Laboratorio de Biotecnología de la Universidad Nacional Federico Villarreal, Lima, Perú.

  • Rodolfo Zenaido Velazco-Peña, Laboratorio de SANIPES

    Biólogo, miembro del Laboratorio de Sanidad Acuícola del Callao, SANIPES, Lima, Perú.

  • Fredy Virgilio Salinas-Meléndez, Universidad Nacional Federico Villarreal

    Doctor en Salud Pública. Docente de la Facultad de Ciencias Naturales y Matemática.  Miembro del Laboratorio de Investigación en Biotecnología, Universidad Nacional Federico Villarreal, Lima, Perú.

  • María Elena Rodrigo-Rojas, Universidad Nacional Federico Villarreal

    Doctora en Educación, Magíster en Bioquímica y en Microbiología. Docente de la Facultad de Ciencias Naturales y Matemática y miembro del Laboratorio de Investigación en Biotecnología de la Universidad Nacional Federico Villarreal, Lima, Perú.

  • Ramses Salas-Asencios, Universidad Nacional Federico Villarreal

    Magister en Bioquímica y en Docencia Universitaria.  Docente de la Facultad de Ciencias Naturales y Matemática. Responsable del Laboratorio de Investigación en Biotecnología, Universidad Nacional Federico Villarreal, Lima, Perú

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Published

2026-04-09

Issue

Section

Scientific articles

How to Cite

Delgado-Olivares, L. G., Osorio-Guevara, V. L., Velazco-Peña, R. Z., Salinas-Meléndez, F. V., Rodrigo-Rojas, M. E., & Salas-Asencios, R. (2026). Nucleotide changes in Vibrio parahaemolyticus plasmids isolated from affected shrimp by the acute Hepatopancreatic Necrosis Disease (AHPND) in Tumbes (Peru). Revista Ciencias Marinas Y Costeras, 18(1), 57-65. https://doi.org/10.15359/revmar.18-1-3