Photoprotective and photorepair action of marine angiosperm extracts, <i>Thalassia testudinum</i> Banks ex König (Hyrocharitacea) and <i>Syringodium filiforme</i> Kützing (Cymodoceaceae)

  • Adrián Fagundo Mollineda Departamento de Farmacología Centro de Bioproductos Marinos (CEBIMAR)
  • María Rodríguez García Centro de Bioproductos Marinos (CEBIMAR) Departamento de Farmacología
  • Kethia L. González García Centro de Bioproductos Marinos (CEBIMAR) Departamento de Química
  • Olga Valdés Iglesias Centro de Bioproductos Marinos (CEBIMAR) Departamento de Química
  • Yasnay Hernández Rivera Centro de Bioproductos Marinos (CEBIMAR) Departamento de Química
  • Ángel R. Concepción Alfonso Instituto Superior de Ciencias Médicas “Victoria de Girón”
  • Odalys Valdés Martínez Departamento de Control Biológico del CIDEM
Keywords: Thalassia, Syringodium, radiation, photoprotection, skin

Abstract

Previous studies with the aqueous-ethanol extracts obtained from the marine angiosperms T. testudinum and S. filiforme have shown their high polyphenolic content and marked antioxidant capacity. This study describes the effects of the topical application of the aqueous-ethanol extracts of T. testudinum and S. filiforme leaves against acute UVB-induced damage. The phanerogams used were collected 3-4m deep in La Habana’s northwestern coast. Five experimental groups were created for the administration of the treatment. The effect was evaluated in in vivo assays, radiating the skin of the dorsal region of albino mice with UVB (dose: 1.21x103 Jxcm2) for six minutes. Before or after UVB irradiation, animals received topical treatment with the extracts at doses of both angiosperms 500μg x cm2 on their skin. Significant differences were observed (P ≤ 0.05) between groups: T. testudinum, S. filiforme, irradiated subjects, and “placebo”. T. testudinum and S. filiforme extracts reduce macroscopic damage caused by UVB radiation in irradiated skins on preventive and photodamage models. In addition, these extracts show protective and repair effects against UVB radiation damage, which could be related to their antioxidant action.

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Published
2015-12-18
How to Cite
Fagundo Mollineda, A., Rodríguez García, M., González García, K. L., Valdés Iglesias, O., Hernández Rivera, Y., Concepción Alfonso, Ángel R., & Valdés Martínez, O. (2015). Photoprotective and photorepair action of marine angiosperm extracts, <i>Thalassia testudinum</i> Banks ex König (Hyrocharitacea) and <i>Syringodium filiforme</i&gt; Kützing (Cymodoceaceae). Journal of Marine and Coastal Sciences, 8(1), 51-62. https://doi.org/10.15359/revmar.8-1.4

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