Identificación de lignanas en hojas de Rollinia mucosa (JACQ) bail. Annonaceae (ING)

Authors

  • Juan R. Villegas Laboratorio de Productos Naturales, Departamento de Química (UNA) , Costa Rica Author
  • Marco Calvo Laboratorio de Productos Naturales, Departamento de Química (UNA) , Costa Rica Author
  • Ian Castro Gamboa Laboratorio de Productos Naturales, Departamento de Química (UNA) , Costa Rica Author
  • Óscar Castro C. Laboratorio de Productos Naturales, Departamento de Química (UNA) , Costa Rica Author

Keywords:

Lignanas, Hojas de Rollinia, Annonaceae

Abstract

Ethanolic extract obtained by maceration of Rollina mucosa leaves was partitioned between hexane, chloroform and ethyl acetate. Samples of all extracts, including the  remanent hydroalcoholic extract, were diluted in ethanol to final concentration of 100μg/mL. These samples were submitted to the Brine shrimp (Artemia salina) lethality assay and only the chloroform extract showed market toxicity. This extract was purified by chromatographic methods and yielded, as mainly compounds, two known lignans: epiudesmine 2 and eudesmine 3, which were identified on the basis of spectral studies ( 1H NMR and 13C NMR). These compounds gave a very low ED50 value in the Brine shrimp lethality assay. Aporphine and oxoaporphine alkaloids have been reported in leaves of this plant, however, any alkaloids could not be detected in our extracts.

Downloads

Download data is not yet available.

References

-

Downloads

Published

2001-01-01

Issue

Vol. 18 No. 1 (2001)

Section

Original scientific papers (evaluated by academic peers)

License

Authors who publish with this journal agree to the following terms:

1. Authors guarantee the journal the right to be the first publication of the work as licensed under a Creative Commons License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal https://creativecommons.org/licenses/by-nc-nd/4.0/.

2. Authors can set separate additional agreements for non-exclusive distribution of the version of the work published in the journal (eg, place it in an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.

3. The authors have declared to hold all permissions to use the resources they provided in the paper (images, tables, among others) and assume full responsibility for damages to third parties.

4. The opinions expressed in the paper are the exclusive responsibility of the authors and do not necessarily represent the opinion of the editors or the Universidad Nacional.


Uniciencia Journal and all its productions are under  Creative Commons Atribución-NoComercial-SinDerivadas 4.0 Unported.

There is neither fee for access nor Article Processing Charge (APC)

How to Cite

Villegas, J. R., Calvo, M., Castro Gamboa, I., & Castro C., Óscar. (2001). Identificación de lignanas en hojas de Rollinia mucosa (JACQ) bail. Annonaceae (ING). Uniciencia, 18(1), 39-42. https://www.revistas.una.ac.cr/index.php/uniciencia/article/view/5713